College football odds, picks, predictions for Week 6, 2026: Computer likes Nebraska, Arkansas

The Week 6 college football schedule brings at least one matchup every night, which started on Tuesday and runs through the full Saturday slate. The highlight is the top-10 SEC battle on Saturday between No. 2 Georgia and No. 6 Alabama in Tuscaloosa, Ala. Both traditional powers are off to impressive undefeated starts, and the Week 6 college football odds show virtually no gap between them as Alabama is -1.5 at home after opening as 2.5-point underdogs. Both teams are 4-1 against the spread this season, while Bama has taken three of the last four matchups. Claim the latest Polymarket promo code CBSSPORTS to get a $25 bonus after $10 in trades:

Other Week 6 college football lines of note include Oregon (-11.5) vs. UCLA, as the Ducks will be without QB Dante Moore (concussion), Texas (-8.5) vs. Oklahoma in the Red River Rivalry and LSU (-8.5) at Kentucky. There's also a matchup of undefeated Big Ten squads as No. 7 Indiana visits Nebraska (+7.5), with the Hoosiers seeking a 6-0 start for the third straight year. Before locking in any Week 6 college football picks on these games or others, be sure to see the latest college football predictions…

Original source: https://www.cbssports.com/