2026 NFL Week 2 early odds: Bills favored over Lions as Buffalo opens new stadium, Eagles road favorites

The NFL is back in full force! The opening slate was jam-packed with storylines. If you wanted points, look no further than Bears-Panthers, who combined for 96 in their opening clash. You wanted upsets? We had those too. Namely, the Cardinals pulling off the outright win over the Chargers on the road, while the Jets went down to Tennessee and beat the Titans. Anything you wanted, Week 1 probably had you covered. Now, the train keeps moving as we eye Week 2.

The Week 2 slate is just as juicy as Week 1 by the looks of it. We get things started with the Lions and Bills squaring off on Thursday night from Buffalo's brand-new Highmark Stadium. Then, we have five divisional matchups on the Sunday slate along with a few tantalizing conference bouts, including Bengals-Texans and Jaguars-Broncos.

As we begin our prep for Week 2, let's take our first look at the betting odds to see who the oddsmakers have coming out on top and what shootouts could occur across the league.

All lines via DraftKings; all games on Sunday unless noted

Buffalo opens up the new Highmark Stadium on Thursday night when they play host to the Detroit…

Original source: https://www.cbssports.com/