Chiefs vs. Broncos prediction, odds, time: ‘Monday Night Football’ Week 1 NFL picks by proven model

The Kansas City Chiefs look to rebound from a rare non-playoff year when they kick off the 2026 season against the defending AFC West champion Denver Broncos on 'Monday Night Football' to conclude the Week 1 NFL schedule. After winning the AFC West for nine consecutive seasons and reaching the Super Bowl in five of six seasons, Kansas City slumped to 6-11 in 2025. Denver, meanwhile, was 14-3 last season and earned its first division title since 2015. The Broncos reached the AFC Championship Game where they dropped a 10-7 decision to the New England Patriots. Claim the latest Polymarket promo code CBSSPORTS to get a $50 bonus after $10 in trades:

Kickoff is at 8:15 p.m. ET from Arrowhead Stadium in Kansas City, Mo. The latest Broncos vs. Chiefs odds have Kansas City as 2.5-point favorites, while the over/under for total points scored is 42.5, down a point from the opener. Offensive lineman Josh Simmons (back) and defensive back Chamarri Conner (knee) are both inactive for Kansas City. Before making any Chiefs vs. Broncos picks, be sure to see the NFL predictions from SportsLine's projection model.

The model, which simulates every NFL game 10,000 times, is up well over…

Original source: https://www.cbssports.com/