Week 2 2026 bold predictions: Giants to upset Rams, tanking Dolphins cover against 49ers

The NFL never fails to surprise, despite so many entering a new season thinking they know what's going to happen.

Just take a look at Week 1. No one had the Arizona Cardinals upsetting the Los Angeles Chargers 26-14 on the road, and almost no one had the preseason Super Bowl favorite Los Angeles Rams getting smoked in Australia by the San Francisco 49ers, 27-7.

To kick off Week 2, the Buffalo Bills thumped the Detroit Lions 41-31 in a game in which they led 21-0. Not a bad way to open their new home at Highmark Stadium. The football world knew the Detroit Lions defense could be rough to start 2026 with injuries to both safety Brian Branch and safety Kerby Joseph, but no one really knew how rough it could be. The 2026 Lions are the second squad in team history to allow 70-plus points and 900-plus total yards in their first two games, along with their 2008 team that went 0-16. A truly unimaginable start to a new year.

So what other crazy happenings could go down in Week 2? Let's take a look with five bold predictions.

The Los Angeles Rams are a perfect 4-0 against…

Original source: https://www.cbssports.com/