Bills vs. Rams prediction, odds, time: ‘Monday Night Football’ picks from proven model

In a possible Super Bowl preview, the Buffalo Bills clash with the Los Angeles Rams on 'Monday Night Football.' Buffalo is coming off a 29-26 loss to the New England Patriots in Week 4, while Los Angeles defeated the Philadelphia Eagles 24-20. The Bills (3-1), who lead the AFC East, are 1-0 on the road this season. The Rams (2-2), who are third in the NFC West, are just 1-1 as the home team in 2026. Aaron Donald (back) is set to return after missing the past two games. Wide receiver D.J. Moore (shoulder) is questionable for Buffalo, while defensive lineman Ed Oliver (knee) is out. Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code CBSSPORTS55:

Kickoff is set for 8:15 p.m. ET from SoFi Stadium in Inglewood, Calif. The latest Bills vs. Rams odds have Los Angeles as a 3.5-point favorites. The over/under for total points scored is 55.5, up a point in the hours leading up to the start time. Before making any Rams vs. Bills picks, be sure to see the 'Monday Night Football' predictions from SportsLine's proven model.

The model, which simulates every NFL game…

Original source: https://www.cbssports.com/