Patriots vs. Seahawks predictions, odds, time: 2026 NFL Kickoff Game picks by model on 53-37 run

The 2026 NFL Kickoff Game will feature the same matchup which closed out last season as the Super Bowl champion Seattle Seahawks host the New England Patriots. The contest takes place on Wednesday, Sep. 9, marking the second time that the NFL Kickoff Game won't be held on a Thursday. Seattle is coming off a 14-3 regular season, which culminated in a 29-13 victory over the Pats in The Big Game. New England also went 14-3 in the regular season in Mike Vrabel's first year as head coach of the team. New England running back TreVeyon Henderson (ankle) has been ruled out. Visit our DraftKings promo code review and get $200 in bonus bets as a new user after $5+ in wagers here:

Kickoff is set for 8:20 p.m. ET from Lumen Field in Seattle. The latest Seahawks vs. Patriots odds have Seattle as a 3.5-point favorite as the line has held steady since opening. The over/under for total points is at 44.5. Before making any Patriots vs. Seahawks picks or 2026 NFL Kickoff Game predictions, be sure to see what the SportsLine projection model has to say.

The model, which simulates every NFL game 10,000 times, is up well…

Original source: https://www.cbssports.com/